Idelalisib 150 mg Tablet

Overview

Ideenat tablet is an advanced antineoplastic medication containing Idelalisib 150 mg or Idelalisib 100 mg, a PI3K inhibitor. It is specifically designed for adults battling chronic lymphocytic leukemia (CLL) in combination with Rituximab.

This treatment is recommended for patients who have undergone previous therapies or whose cancer cells have genetic mutations such as 17p deletion or TP53 mutation. Additionally, it is prescribed as a monotherapy for follicular lymphoma in adults. However, it is not suitable for patients under 18 years.

Precautions Before Using

Avoid taking it if you have a known allergy to Idelalisib or sunset yellow FCF. Consult your doctor if you have pre-existing conditions such as:

• Liver disorders
• Lung inflammation (pneumonitis)
• Kidney disease
• Intestinal perforation
• Neutropenia (low neutrophil count)
• Severe skin reactions (Stevens-Johnson syndrome)
• Active infections, including hepatitis

Pregnant or breastfeeding women should avoid this medicine. Effective contraception is necessary during treatment and for one month after stopping the medication. Regular blood tests are conducted to monitor possible infections or adverse effects.

Medical Supervision and Dosage Adjustments

Before initiating treatment with it, inform your doctor about any pre-existing medical conditions or ongoing medications. Your physician will assess your respiratory, kidney, and liver function before and during therapy. Dosage adjustments may be required based on your body’s response and potential side effects. Seek immediate medical attention if you experience any unusual symptoms.

Uses

• Chronic lymphocytic leukemia (CLL) in adults
• Follicular lymphoma (as monotherapy)

How it Works

It is a targeted therapy that blocks PI3K delta isoform, which plays a crucial role in B-cell and T-cell function. By inhibiting this enzyme, it disrupts signals that promote cancer cell survival, proliferation, and migration, ultimately leading to cancer cell death.

Drug Interactions

Inform your doctor about any prescription drugs, over-the-counter medications, herbal supplements, or vitamins you are taking. Certain medications, including alfuzosin, pimozide, rifabutin, and others, may interact with it, leading to potential side effects.

Storage Guidelines

• Keep away from children and pets.
• Store in a cool, dry place away from direct sunlight (below 30°C).
• Do not freeze.

How to Take

• Take the tablet exactly as prescribed by your doctor.
• Usually taken twice a day without crushing, chewing, or opening the tablet.
• The dosage is determined based on your age, weight, and disease condition.
• Do not stop taking the medicine unless advised by your doctor.

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